MDM® Filler

The manufacturer of ProDerm fillers is BioPlus Co., Ltd. MDM® technology completed by BioPlus through research and development is its own technology that best deals with bio-material HA.. MDM® technology consists of three main technologies: MBMT, DMCT, and MDAP.

  • MBMT™

    Micro Bead Monophasic technology

  • DMCT™

    Divinyl sulfone multi-crosslink technology

  • MDAP™

    Multiple Degree Amphiphilic Purification

Smart Filler is an Approved Medical Product

Four Advantages of MDM® fillers

“Smart Derm” is an official exclusive distributor of hyaluronic acid fillers - ProDerm. Proderm – dermal fillers with world-class MDM® Technology.


Created by Bioplus’ Patent Technology

High-Quality FILLER

Recognized First by the world

Perfect-Safe FILLER

to fundamentally block side effects

High-Class Premium

Expensive FILLER

Manufacturing Method and Quality Characteristic of MDM® fillers


Micro Bead Monophasic Technology

Mono-Phasic filler manufacture by aggregating Micro-Bead

Free Viscoelasticity adjustment based on purpose of use


Divinyl sulfone Multi-Crosslink Technology

Full bridge with Multi Cross-link using DVS

Excellent viscoelasticity and molding power


Multiple Degree Amphiphilic Purification

Manufacture pure and safe products

with multi-stage refining technology